logo-01.png

文字サイズ変更  テキストサイズ 小 |中 |大 |



トップページ > 人物紹介・研究実績

自己紹介・研究実績-01.png

人物紹介

役職
東北大学 災害科学国際研究所 災害医学研究部門 災害医療情報学分野 教授
東北大学病院 メディカルITセンター 副部長
東北大学病院 循環器内科
資格
日本内科学会認定内科医、日本循環器学会専門医
所属学会
日本循環器学会、日本内科学会、日本心臓病学会、日本バイオインフォマティクス学会(東北地域部会長H19-22)、
日本心血管インターベンション学会、日本生化学会、日本医療情報学会、
American Heart Association、American Medical Informatics Association
活動内容
【診療】外来診療(虚血グループ)
【研究】医療情報システム構築・運営・管理
     データベースシステム開発
     クリニカルバイオインフォマティクス
【教育】学生・研修医への指導、医療情報学講義(東北福祉大)
主な受賞歴
2013年(平成25年) 国際医療情報学会MedInfo2013優秀演題賞

論文

Nakayama M, Inoue R. The need for standardization of allergy information in electronic medical record among Japanese hospitals. Stud Health Technol Inform.2014;205:1257.

Nihei T, Takahashi J, Tsuburaya R, Ito Y, Shiroto T, Hao K, Takagi Y, Matsumoto Y, Nakayama M, Miyata S, Sakata Y, Ito K, Shimokawa H. Circadian Variation of Rho-Kinase Activity in Circulating Leukocytes of Patients With Vasospastic Angina. Circ J. 2014 Mar 27.

Hao K, Takahashi J, Ito K, Miyata S, Sakata Y, Nihei T, Tsuburaya R, Shiroto T, Ito Y, Matsumoto Y, Nakayama M, Yasuda S, Shimokawa H; Miyagi AMI Registry Study Investigators. Emergency care of acute myocardial infarction and the great East Japan earthquake disaster. Circ J. 2014;78(3):634-43.

Nakayama M, Takeda M, Asaumi Y, Shimokawa H. Identification and visualization of stimulus-specific transcriptional activity in cardiac hypertrophy in mice. Int J Cardiovasc Imaging. 2014 Jan;30(1):211-9.

Miura M, Sakata Y, Miyata S, Nochioka K, Takada T, Tadaki S, Takahashi J, Shiba N, Shimokawa H; CHART-2 Investigators. Usefulness of combined risk stratification with heart rate and systolic blood pressure in the management of chronic heart failure. A report from the CHART-2 study. Circ J.2013;77(12):2954-62.

Nakayama M, Shimokawa H. Evaluation of an electrocardiogram on QR code. Stud Health Technol Inform. 2013;192:1020.

Satoh K, Fukumoto Y, Sugimura K, Miura Y, Aoki T, Nochioka K, Tatebe S, Miyamichi-Yamamoto S, Shimizu T, Osaki S, Takagi Y, Tsuburaya R, Ito Y, Matsumoto Y, Nakayama M, Takeda M, Takahashi J, Ito K, Yasuda S, Shimokawa H. Plasma cyclophilin A is a novel biomarker for coronary artery disease. Circ J. 2013;77(2):447-55.

Nihei T, Takahashi J, Kikuchi Y, Takagi Y, Hao K, Tsuburaya R, Shiroto T, Ito Y, Matsumoto Y, Nakayama M, Ito K, Yasuda S, Shimokawa H. Enhanced Rho-kinase activity in patients with vasospastic angina after the Great East Japan Earthquake. Circ J. 2012;76(12):2892-4.

Aizawa K, Yasuda S, Takahashi J, Takii T, Kikuchi Y, Tsuburaya R, Ito Y, Ito K, Nakayama M, Takeda M, Shimokawa H. Involvement of rho-kinase activation in the pathogenesis of coronary hyperconstricting responses induced by drug-eluting stents in patients with coronary artery disease. Circ J. 2012;76(11):2552-60.

Hao K, Yasuda S, Takii T, Ito Y, Takahashi J, Ito K, Nakayama M, Shiba N, Fukumoto Y, Shimokawa H; MIYAGI-AMI Study Investigators. Urbanization, life style changes and the incidence/in-hospital mortality of acute myocardial infarction in Japan: report from the MIYAGI-AMI Registry Study. Circ J. 2012;76(5):1136-44.

Kikuchi Y, Yasuda S, Aizawa K, Tsuburaya R, Ito Y, Takeda M, Nakayama M, Ito K, Takahashi J, Shimokawa H. Enhanced Rho-kinase activity in circulating neutrophils of patients with vasospastic angina: a possible biomarker for diagnosis and disease activity assessment. J Am Coll Cardiol. 2011 Sep 13;58(12):1231-7.

Aoki T, Fukumoto Y, Sugimura K, Oikawa M, Satoh K, Nakano M, Nakayama M, Shimokawa H. Prognostic impact of myocardial interstitial fibrosis in non-ischemic heart failure. -Comparison between preserved and reduced ejection fraction heart failure.-. Circ J. 2011;75(11):2605-13.

Nakayama M, Osaki S, Shimokawa H. Validation of mortality risk stratification models for cardiovascular disease. Am J Cardiol. 2011 Aug 1;108(3):391-6.

Shiba N, Nochioka K, Miura M, Kohno H, Shimokawa H; CHART-2 Investigators. Trend of westernization of etiology and clinical characteristics of heart failure patients in Japan--first report from the CHART-2 study. Circ J.2011;75(4):823-33.):944-52.

Kikuchi Y, Ito K, Ito Y, Shiroto T, Tsuburaya R, Aizawa K, Hao K, Fukumoto Y, Takahashi J, Takeda M, Nakayama M, Yasuda S, Kuriyama S, Tsuji I, Shimokawa H. Double-blind and placebo-controlled study of the effectiveness and safety of extracorporeal cardiac shock wave therapy for severe angina pectoris. Circ J.
2010 Mar;74(3):589-91.

Takagi Y, Yasuda S, Takahashi J, Takeda M, Nakayama M, Ito K, Hirose M, Wakayama Y, Fukuda K, Shimokawa H. Importance of dual induction tests for coronary vasospasm and ventricular fibrillation in patients surviving out-of-hospital cardiac arrest. Circ J. 2009 Apr;73(4):767-9.

Shibuya A, Nakayama M, Inoue R, Imai Y, Kondo Y. Decision making and hysician prescribing characteristics: a pilot study of Japanese physicians. AMIA Annu Symp Proc. 2009 Nov 14;2009:604-8.e.

Nakayama M, Shibuya A, Inoue R, Kondo Y. Automated measurement of cardiothoracic ratio using an R package. AMIA Annu Symp Proc. 2008 Nov 6:1064.

Inoue R, Nakayama M, Shibuya A, Ohkubo T, Asayama K, Metoki H, Tamura T, Kondo Y, Imai Y. Large scale intervention study to hypertension with information technology: Hypertension objective treatment based on Measurement by Electrical Devices of Blood Pressure (HOMED-BP) Study. AMIA Annu Symp Proc. 2008 Nov 6:986.

Shibuya A, Nakayama M, Inoue R, Endo A, Imai Y, Kondo Y. The Medical Cells: for the spread of clinical knowledge management. AMIA Annu Symp Proc. 2008 Nov 6:1130.

Shibuya A, Inoue R, Ohsaga A, Nakayama M, Endo A, Kondo Y. A new approach to medical and clinical knowledge management by using the Medical Cells strategy. AMIA Annu Symp Proc. 2007 Oct 11:1113.

Nakayama M, Shibuya A, Inoue R, Ohsaga A, Kondo Y. An XML-based integration method for different types of patient data in cardiology. AMIA Annu Symp Proc. 2007 Oct 11:1057.

Takahashi K, Komaru T, Takeda S, Takeda M, Koshida R, Nakayama M, Kokusho Y, Kawakami Y, Yamaguchi N, Miyazawa T, Shimokawa H, Shirato K. gamma-tocopherol, but not alpha-tocopherol, potently inhibits neointimal formation induced by vascular injury in insulin resistant rats. J Mol Cell Cardiol. 2006 Sep;41(3):544-54. Epub 2006 Jul 31.

Sato K, Komaru T, Shioiri H, Takeda S, Takahashi K, Kanatsuka H, Nakayama M, Shirato K. Hypercholesterolemia impairs transduction of vasodilator signals derived from ischemic myocardium: myocardium-microvessel cross-talk. Arterioscler Thromb Vasc Biol. 2004 Nov;24(11):2034-9.

Shibahara S, Nakayama M, Kitamuro T, Udono-Fujimori R, Takahashi K. Repression of heme oxygenase-1 expression as a defense strategy in humans. Exp Biol Med (Maywood). 2003 May;228(5):472-3.

Kitamuro T, Takahashi K, Ogawa K, Udono-Fujimori R, Takeda K, Furuyama K, Nakayama M, Sun J, Fujita H, Hida W, Hattori T, Shirato K, Igarashi K, Shibahara S. Bach1 functions as a hypoxia-inducible repressor for the heme oxygenase-1 gene in human cells. J Biol Chem. 2003 Mar 14;278(11):9125-33.

Matsuda Y Sakurai K, Nakayama M, Inoue K, Kyouno H, Kitaoka S. Three cases of Takotsubo cardiomyopathy--reversible left ventricular dysfunction. Nippon Naika Gakkai Zasshi,91(2),(2002),740-742.

Kitamuro T, Takahashi K, Totsune K, Nakayama M, Murakami O, Hida W, Shirato K, Shibahara S. Differential expression of adrenomedullin and its receptor component, receptor activity modifying protein (RAMP) 2 during hypoxia in cultured human neuroblastoma cells. Peptides,22(11),(2001),1795-1801.

Nakayama M, Takahashi K, Komaru T, Fukuchi M, Shioiri H, Kitamuro T, Shirato K, Yamaguchi T, Suematsu M, Shibahara S. Increased expression of heme oxygenase-1 and bilirubin accumulation in foam cells of rabbit atherosclerotic lesions. Arterioscler Thromb Vasc Biol,21(8),(2001),1373-1377.

Udono T, Takahashi K, Nakayama M, Yoshinoya A, Totsune K, Murakami O, Durlu Y K, Tamai M, Shibahara S. Induction of adrenomedullin by hypoxia in cultured retinal pigment epithelial cells. Invest Ophthalmol Vis Sci,42(5),(2001),1080-1086.

Kitamuro T, Takahashi K, Nakayama M, Murakami O, Hida W, Shirato K, Shibahara S. Induction of adrenomedullin during hypoxia in cultured human glioblastoma cells. J Neurochem,75(5),(2000),1826-1833.

Udono T, Takahashi K, Nakayama M, Murakami O, Durlu Y K, Tamai M, Shibahara S. Adrenomedullin in cultured human retinal pigment epithelial cells. Invest Ophthalmol Vis Sci,41(7),(2000),1962-1970.

Nakayama M, Takahashi K, Kitamuro T, Murakami O, Shirato K, Shibahara S. Transcriptional control of adrenomedullin induction by phorbol ester in human monocytic leukemia cells. Eur J Biochem,267(12),(2000),3559-3566.

Nakayama M, Takahashi K, Kitamuro T, Yasumoto K, Katayose D, Shirato K, Fujii-Kuriyama Y, Shibahara S. Repression of heme oxygenase-1 by hypoxia in vascular endothelial cells. Biochem Biophys Res Commun,271(3),(2000),665-671.

Takahashi K, Nakayama M, Totsune K, Murakami O, Sone M, Kitamuro T, Yoshinoya A, Shibahara S. Increased secretion of adrenomedullin from cultured human astrocytes by cytokines. J Neurochem,74(1),(2000),99-103.

Nakayama M, Takahashi K, Murakami O, Murakami H, Sasano H, Shirato K, Shibahara S Adrenomedullin in monocytes and macrophages: possible involvement of macrophage-derived adrenomedullin in atherogenesis. Clin Sci (Lond),97(2),(1999),247-251

Hara E, Takahashi K, Takeda K, Nakayama M, Yoshizawa M, Fujita H, Shirato K, Shibahara S. Induction of heme oxygenase-1 as a response in sensing the signals evoked by distinct nitric oxide donors. Biochem Pharmacol,58(2),(1999),227-236.

Takahashi K, Nakayama M, Takeda K, Fujia H, Shibahara S. Suppression of heme oxygenase-1 mRNA expression by interferon-gamma in human glioblastoma cells. J Neurochem,72(6),(1999),2356-2361.

Nakayama M, Takahashi K, Murakami O, Yanai M, Sasaki H, Shirato K, Shibahara S. Production and secretion of adrenomedullin in cultured human alveolar macrophages. Peptides,20(9),(1999),1123-1125.

Nakayama M, Takahashi K, Murakami O, Shirato K, Shibahara S. Induction of adrenomedullin by hypoxia in cultured human coronary artery endothelial cells. Peptides,20(6),(1999),769-772.

Nakayama M, Takahashi K, Hara E, Murakami O, Totsune K, Sone M, Satoh F, Shibahara S Production and secretion of two vasoactive peptides, endothelin-1 and adrenomedullin, by a colorectal adenocarcinoma cell line, DLD-1. J Cardiovasc Pharmacol,31 Suppl 1,(1998),S534-6.

Nakayama M, Takahashi K, Murakami O, Shirato K, Shibahara S. Induction of adrenomedullin by hypoxia and cobalt chloride in human colorectal carcinoma cells. Biochem Biophys Res Commun,243(2),(1998),514-517.

国際学会

2014年
AMIA 2014 Annual Symposium(November 15 - November 19, 2014, Washington DC ,USA)
Nakayama M. Prevalence of a Standardized Storage Format and Next Steps for Clinicians.
2014年
MIE 2014(August31-September3,2014, Istanbul,Turkish)
Nakayama M Inoue R. The Need for Standardization of Allergy Information in Electronic Medical Record Among Japanese Hospitals.
2013
AMIA 2013 Annual Symposium (November16-20, 2013 Washington, DC, USA)
Nakayama M, Shimokawa H. Usefulness of MFER for the diagnosis of vasospastic angina with coronary spasm provocation test during coronary angiography.
2013
MEDINFO 2013 (August20-23, 2013 Copenhagen, Denmark)
Nakayama M, Shimokawa H. Evaluation of an Electrocardiogram on QR code. (Distinguished Poster Award 受賞)

国内学会

2014年
第34回 医療情報学連合大会(11月6-8日、2014年、千葉)
【公募企画】中山 雅晴「アレルギー情報の入力・出力様式の現状-全国アンケート調査の結果から-」
2014年
第12回 Asia Pacific Conference on Disaster Medicine(9月17-19日、2014年、東京)
【ポスター】中山 雅晴「Minimum Patient Data Should Include an Electrocardiogram」
2014年
第31回 日本心電学会学術集会合同学術大会 (7月22-25日、2014年、東京)
【特別シンポジウム】中山 雅晴:Practical issues in the development of cardiovascular disease databases for cardiovascular disease
2014年
第5回 安全・安心な生活のための情報5通信システム(ICSSSL)研究会(2014年6月13日、2014年、仙台)
【招待講演】中山 雅晴「診療情報バックアップと標準保存形式」
2014年
第18回 日本医療情報学春季学術大会(6月5-7日、2014年、岡山)
【ポスター】井上 隆輔、中山 雅晴、中谷 純:病院情報システムにおける薬剤禁忌情報の取り扱い
2014年
第78回 日本循環器学会学術集会(3月21日‐23日、2014年、東京)
【口演】中山 雅晴、竹花 一哉、興梠 貴英、武田 和大、下川 宏明:Data transition platforms in hospital information system should be established to construct data-base with information communication technology.
2014年
第78回 日本循環器学会学術集会(3月21日‐23日、2014年、東京)
【ファイアサイドセミナー】中山 雅晴 IHE-J :循環器病データベース構築のための医療機器データ連携の有用性
2013年
第36回 日本分子生物学会(12月3日‐6日、2013年、神戸)
【ワークショップ】中山 雅晴、宮田 敏、下川 宏明:臨床医にとって必要なバイオインフォマティシャン・統計専門家
2013年
第33回 医療情報学連合大会・第14回日本医療情報学会学術大会(11月21‐23日、2013年、神戸)
【パネルディスカッション】中山 雅晴:アレルギー情報の標準化をめざして―アレルギー情報の共有には何が必要かー全国アンケート調査より